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Digital Spatial Profiling Links Beta-2-microglobulin Expression with Immune Checkpoint Blockade Outcomes in Head and Neck Squamous Cell Carcinoma

Programmed cell death protein‐1 (PD-1)-targeted immunotherapy is approved for recurrent or metastatic head and neck squamous cell carcinoma (R/M HNSCC) treatment. Although its efficacy correlates with PD-L1 expression, response is limited even among positive cases. We employed digital spatial profil...

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Detalles Bibliográficos
Autores principales: Gavrielatou, Niki, Vathiotis, Ioannis, Aung, Thazin Nwe, Shafi, Saba, Burela, Sneha, Fernandez, Aileen I., Moutafi, Myrto, Burtness, Barbara, Economopoulou, Panagiota, Anastasiou, Maria, Foukas, Periklis, Psyrri, Amanda, Rimm, David L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10088911/
https://www.ncbi.nlm.nih.gov/pubmed/37057033
http://dx.doi.org/10.1158/2767-9764.CRC-22-0299