De novo design of small beta barrel proteins

Small beta barrel proteins are attractive targets for computational design because of their considerable functional diversity despite their very small size (<70 amino acids). However, there are considerable challenges to designing such structures, and there has been little success thus far. Becau...

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Detalles Bibliográficos
Autores principales: Kim, David E., Jensen, Davin R., Feldman, David, Tischer, Doug, Saleem, Ayesha, Chow, Cameron M., Li, Xinting, Carter, Lauren, Milles, Lukas, Nguyen, Hannah, Kang, Alex, Bera, Asim K., Peterson, Francis C., Volkman, Brian F., Ovchinnikov, Sergey, Baker, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10089152/
https://www.ncbi.nlm.nih.gov/pubmed/36897987
http://dx.doi.org/10.1073/pnas.2207974120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10089152/
https://www.ncbi.nlm.nih.gov/pubmed/36897987
http://dx.doi.org/10.1073/pnas.2207974120

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