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Immune cells use active tugging forces to distinguish affinity and accelerate evolution

Cells are known to exert forces to sense their physical surroundings for guidance of motion and fate decisions. Here, we propose that cells might do mechanical work to drive their own evolution, taking inspiration from the adaptive immune system. Growing evidence indicates that immune B cells—capabl...

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Detalles Bibliográficos
Autores principales: Jiang, Hongda, Wang, Shenshen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10089171/
https://www.ncbi.nlm.nih.gov/pubmed/36897986
http://dx.doi.org/10.1073/pnas.2213067120