Inflammation differentially controls transport of depolarizing Nav versus hyperpolarizing Kv channels to drive rat nociceptor activity

Inflammation causes pain by shifting the balance of ionic currents in nociceptors toward depolarization, leading to hyperexcitability. The ensemble of ion channels within the plasma membrane is regulated by processes including biogenesis, transport, and degradation. Thus, alterations in ion channel...

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Detalles Bibliográficos
Autores principales: Higerd-Rusli, Grant P., Tyagi, Sidharth, Baker, Christopher A., Liu, Shujun, Dib-Hajj, Fadia B., Dib-Hajj, Sulayman D., Waxman, Stephen G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10089179/
https://www.ncbi.nlm.nih.gov/pubmed/36897973
http://dx.doi.org/10.1073/pnas.2215417120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10089179/
https://www.ncbi.nlm.nih.gov/pubmed/36897973
http://dx.doi.org/10.1073/pnas.2215417120

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