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Cryo-EM structure of the human chemerin receptor 1–Gi protein complex bound to the C-terminal nonapeptide of chemerin

Chemerin is a processed protein that acts on G protein-coupled receptors (GPCRs) for its chemotactic and adipokine activities. The biologically active chemerin (chemerin 21-157) results from proteolytic cleavage of prochemerin and uses its C-terminal peptide containing the sequence YFPGQFAFS for rec...

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Detalles Bibliográficos
Autores principales: Wang, Junlin, Chen, Geng, Liao, Qiwen, Lyu, Wenping, Liu, Aijun, Zhu, Lizhe, Du, Yang, Ye, Richard D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10089180/
https://www.ncbi.nlm.nih.gov/pubmed/36881626
http://dx.doi.org/10.1073/pnas.2214324120