MYC-driven synthesis of Siglec ligands is a glycoimmune checkpoint

The Siglecs (sialic acid-binding immunoglobulin-like lectins) are glycoimmune checkpoint receptors that suppress immune cell activation upon engagement of cognate sialoglycan ligands. The cellular drivers underlying Siglec ligand production on cancer cells are poorly understood. We find the MYC onco...

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Detalles Bibliográficos
Autores principales: Smith, Benjamin A. H., Deutzmann, Anja, Correa, Kristina M., Delaveris, Corleone S., Dhanasekaran, Renumathy, Dove, Christopher G., Sullivan, Delaney K., Wisnovsky, Simon, Stark, Jessica C., Pluvinage, John V., Swaminathan, Srividya, Riley, Nicholas M., Rajan, Anand, Majeti, Ravindra, Felsher, Dean W., Bertozzi, Carolyn R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10089186/
https://www.ncbi.nlm.nih.gov/pubmed/36897988
http://dx.doi.org/10.1073/pnas.2215376120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10089186/
https://www.ncbi.nlm.nih.gov/pubmed/36897988
http://dx.doi.org/10.1073/pnas.2215376120

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