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Shear rate sensitizes bacterial pathogens to H(2)O(2) stress

Cells regularly experience fluid flow in natural systems. However, most experimental systems rely on batch cell culture and fail to consider the effect of flow-driven dynamics on cell physiology. Using microfluidics and single-cell imaging, we discover that the interplay of physical shear rate (a me...

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Detalles Bibliográficos
Autores principales: Padron, Gilberto C., Shuppara, Alexander M., Sharma, Anuradha, Koch, Matthias D., Palalay, Jessica-Jae S., Radin, Jana N., Kehl-Fie, Thomas E., Imlay, James A., Sanfilippo, Joseph E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10089187/
https://www.ncbi.nlm.nih.gov/pubmed/36888662
http://dx.doi.org/10.1073/pnas.2216774120