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Shear rate sensitizes bacterial pathogens to H(2)O(2) stress
Cells regularly experience fluid flow in natural systems. However, most experimental systems rely on batch cell culture and fail to consider the effect of flow-driven dynamics on cell physiology. Using microfluidics and single-cell imaging, we discover that the interplay of physical shear rate (a me...
Autores principales: | Padron, Gilberto C., Shuppara, Alexander M., Sharma, Anuradha, Koch, Matthias D., Palalay, Jessica-Jae S., Radin, Jana N., Kehl-Fie, Thomas E., Imlay, James A., Sanfilippo, Joseph E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10089187/ https://www.ncbi.nlm.nih.gov/pubmed/36888662 http://dx.doi.org/10.1073/pnas.2216774120 |
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