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SIK3–HDAC4 in the suprachiasmatic nucleus regulates the timing of arousal at the dark onset and circadian period in mice

Mammals exhibit circadian cycles of sleep and wakefulness under the control of the suprachiasmatic nucleus (SCN), such as the strong arousal phase-locked to the beginning of the dark phase in laboratory mice. Here, we demonstrate that salt-inducible kinase 3 (SIK3) deficiency in gamma-aminobutyric a...

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Detalles Bibliográficos
Autores principales: Asano, Fuyuki, Kim, Staci J., Fujiyama, Tomoyuki, Miyoshi, Chika, Hotta-Hirashima, Noriko, Asama, Nodoka, Iwasaki, Kanako, Kakizaki, Miyo, Mizuno, Seiya, Mieda, Michihiro, Sugiyama, Fumihiro, Takahashi, Satoru, Shi, Shoi, Hirano, Arisa, Funato, Hiromasa, Yanagisawa, Masashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10089210/
https://www.ncbi.nlm.nih.gov/pubmed/36877841
http://dx.doi.org/10.1073/pnas.2218209120