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CENP-I directly targets centromeric DNA to support CENP-A deposition and centromere maintenance

The enrichment of histone H3 variant CENP-A is the epigenetic mark of centromere and initiates the assembly of the kinetochore at centromere. The kinetochore is a multi-subunit complex that ensures accurate attachment of microtubule centromere and faithful segregation of sister chromatids during mit...

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Detalles Bibliográficos
Autores principales: Hu, Liqiao, Zhao, Congcong, Liu, Mingjie, Liu, Shuaiyu, Ye, Jingjing, Wang, Kehui, Shi, Jinyun, Tian, Wei, He, Xiaojing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10089219/
https://www.ncbi.nlm.nih.gov/pubmed/36888657
http://dx.doi.org/10.1073/pnas.2219170120