Cargando…

The impact of mutation sets in receptor-binding domain of SARS-CoV-2 variants on the stability of RBD–ACE2 complex

Aim: Bioinformatic analysis of mutation sets in receptor-binding domain (RBD) of currently and previously circulating SARS-CoV-2 variants of concern (VOCs) and interest (VOIs) to assess their ability to bind the ACE2 receptor. Methods: In silico sequence and structure-oriented approaches were used t...

Descripción completa

Detalles Bibliográficos
Autores principales: Peka, Mykyta, Balatsky, Viktor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Medicine Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10089296/
https://www.ncbi.nlm.nih.gov/pubmed/37064325
http://dx.doi.org/10.2217/fvl-2022-0152