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Adeno-Associated virus 8 delivers an immunomodulatory peptide to mouse liver more efficiently than to rat liver

Targeting the Kv1.3 potassium channel has proven effective in reducing obesity and the severity of animal models of autoimmune disease. Stichodactyla toxin (ShK), isolated from the sea anemone Stichodactyla helianthus, is a potent blocker of Kv1.3. Several of its analogs are some of the most potent...

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Detalles Bibliográficos
Autores principales: Wang, Yuqing, Hurley, Ayrea, De Giorgi, Marco, Tanner, Mark R., Hu, Rong-Chi, Pennington, Michael W., Lagor, William R., Beeton, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10089316/
https://www.ncbi.nlm.nih.gov/pubmed/37040361
http://dx.doi.org/10.1371/journal.pone.0283996