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Adeno-Associated virus 8 delivers an immunomodulatory peptide to mouse liver more efficiently than to rat liver
Targeting the Kv1.3 potassium channel has proven effective in reducing obesity and the severity of animal models of autoimmune disease. Stichodactyla toxin (ShK), isolated from the sea anemone Stichodactyla helianthus, is a potent blocker of Kv1.3. Several of its analogs are some of the most potent...
Autores principales: | Wang, Yuqing, Hurley, Ayrea, De Giorgi, Marco, Tanner, Mark R., Hu, Rong-Chi, Pennington, Michael W., Lagor, William R., Beeton, Christine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10089316/ https://www.ncbi.nlm.nih.gov/pubmed/37040361 http://dx.doi.org/10.1371/journal.pone.0283996 |
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