Combining phylogeny and coevolution improves the inference of interaction partners among paralogous proteins

Predicting protein-protein interactions from sequences is an important goal of computational biology. Various sources of information can be used to this end. Starting from the sequences of two interacting protein families, one can use phylogeny or residue coevolution to infer which paralogs are spec...

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Detalles Bibliográficos
Autores principales: Gandarilla-Pérez, Carlos A., Pinilla, Sergio, Bitbol, Anne-Florence, Weigt, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10089317/
https://www.ncbi.nlm.nih.gov/pubmed/36996234
http://dx.doi.org/10.1371/journal.pcbi.1011010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10089317/
https://www.ncbi.nlm.nih.gov/pubmed/36996234
http://dx.doi.org/10.1371/journal.pcbi.1011010

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