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Combining phylogeny and coevolution improves the inference of interaction partners among paralogous proteins
Predicting protein-protein interactions from sequences is an important goal of computational biology. Various sources of information can be used to this end. Starting from the sequences of two interacting protein families, one can use phylogeny or residue coevolution to infer which paralogs are spec...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10089317/ https://www.ncbi.nlm.nih.gov/pubmed/36996234 http://dx.doi.org/10.1371/journal.pcbi.1011010 |