Long non-coding RNA HIF1A-As2 and MYC form a double-positive feedback loop to promote cell proliferation and metastasis in KRAS-driven non-small cell lung cancer

Lung cancer is the leading cause of cancer-related deaths worldwide. KRAS is the main oncogenic driver in lung cancer that can be activated by gene mutation or amplification, but whether long non-coding RNAs (lncRNAs) regulate its activation remains unknown. Through gain and loss of function approac...

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Detalles Bibliográficos
Autores principales: Yang, Kaixin, Zhang, Wenyang, Zhong, Linghui, Xiao, Yinan, Sahoo, Sudhakar, Fassan, Matteo, Zeng, Kang, Magee, Peter, Garofalo, Michela, Shi, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10089381/
https://www.ncbi.nlm.nih.gov/pubmed/37041291
http://dx.doi.org/10.1038/s41418-023-01160-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10089381/
https://www.ncbi.nlm.nih.gov/pubmed/37041291
http://dx.doi.org/10.1038/s41418-023-01160-x

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