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Differential Retention of Pfam Domains Contributes to Long-term Evolutionary Trends
Protein domains that emerged more recently in evolution have a higher structural disorder and greater clustering of hydrophobic residues along the primary sequence. It is hard to explain how selection acting via descent with modification could act so slowly as not to saturate over the extraordinaril...
Autores principales: | James, Jennifer E, Nelson, Paul G, Masel, Joanna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10089649/ https://www.ncbi.nlm.nih.gov/pubmed/36947137 http://dx.doi.org/10.1093/molbev/msad073 |
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