OutSingle: a novel method of detecting and injecting outliers in RNA-Seq count data using the optimal hard threshold for singular values

MOTIVATION: Finding outliers in RNA-sequencing (RNA-Seq) gene expression (GE) can help in identifying genes that are aberrant and cause Mendelian disorders. Recently developed models for this task rely on modeling RNA-Seq GE data using the negative binomial distribution (NBD). However, some of those...

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Detalles Bibliográficos
Autores principales: Salkovic, Edin, Sadeghi, Mohammad Amin, Baggag, Abdelkader, Salem, Ahmed Gamal Rashed, Bensmail, Halima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10089674/
https://www.ncbi.nlm.nih.gov/pubmed/36945891
http://dx.doi.org/10.1093/bioinformatics/btad142

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10089674/
https://www.ncbi.nlm.nih.gov/pubmed/36945891
http://dx.doi.org/10.1093/bioinformatics/btad142

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