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Integrating single-cell and bulk RNA sequencing to develop a cancer-associated fibroblast-related signature for immune infiltration prediction and prognosis in lung adenocarcinoma

BACKGROUND: An accumulating amount of studies are highlighting the impacts of cancer-associated fibroblasts (CAFs) on the initiation, metastasis, invasion, and immune evasion of lung cancer. However, it is still unclear how to tailor treatment regimens based on the transcriptomic characteristics of...

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Detalles Bibliográficos
Autores principales: Huang, Xiulin, Xiao, Hui, Shi, Yongxin, Ben, Suqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10089835/
https://www.ncbi.nlm.nih.gov/pubmed/37065583
http://dx.doi.org/10.21037/jtd-23-238