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Experimental characterization of de novo proteins and their unevolved random-sequence counterparts
De novo gene emergence provides a route for new proteins to be formed from previously non-coding DNA. Proteins born in this way are considered random sequences and typically assumed to lack defined structure. While it remains unclear how likely a de novo protein is to assume a soluble and stable ter...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10089919/ https://www.ncbi.nlm.nih.gov/pubmed/37024625 http://dx.doi.org/10.1038/s41559-023-02010-2 |