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State-dependent evolutionary models reveal modes of solid tumour growth

Spatial properties of tumour growth have profound implications for cancer progression, therapeutic resistance and metastasis. Yet, how spatial position governs tumour cell division remains difficult to evaluate in clinical tumours. Here, we demonstrate that faster division on the tumour periphery le...

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Detalles Bibliográficos
Autores principales: Lewinsohn, Maya A., Bedford, Trevor, Müller, Nicola F., Feder, Alison F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10089931/
https://www.ncbi.nlm.nih.gov/pubmed/36894662
http://dx.doi.org/10.1038/s41559-023-02000-4