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Cryo-EM structures of mitochondrial ABC transporter ABCB10 in apo and biliverdin-bound form

ABCB10, a member of ABC transporter superfamily that locates in the inner membrane of mitochondria, plays crucial roles in hemoglobin synthesis, antioxidative stress and stabilization of the iron transporter mitoferrin-1. Recently, it was found that ABCB10 is a mitochondrial biliverdin exporter. How...

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Detalles Bibliográficos
Autores principales: Cao, Sheng, Yang, Yihu, He, Lili, Hang, Yumo, Yan, Xiaodong, Shi, Hui, Wu, Jiaquan, Ouyang, Zhuqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10090120/
https://www.ncbi.nlm.nih.gov/pubmed/37041204
http://dx.doi.org/10.1038/s41467-023-37851-9