PUREE: accurate pan-cancer tumor purity estimation from gene expression data

Tumors are complex masses composed of malignant and non-malignant cells. Variation in tumor purity (proportion of cancer cells in a sample) can both confound integrative analysis and enable studies of tumor heterogeneity. Here we developed PUREE, which uses a weakly supervised learning approach to i...

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Detalles Bibliográficos
Autores principales: Revkov, Egor, Kulshrestha, Tanmay, Sung, Ken Wing-Kin, Skanderup, Anders Jacobsen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10090153/
https://www.ncbi.nlm.nih.gov/pubmed/37041233
http://dx.doi.org/10.1038/s42003-023-04764-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10090153/
https://www.ncbi.nlm.nih.gov/pubmed/37041233
http://dx.doi.org/10.1038/s42003-023-04764-8

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