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Reprogramming of human peripheral blood mononuclear cells into induced mesenchymal stromal cells using non-integrating vectors

Mesenchymal stromal cells (MSCs) have great value in cell therapies. The MSC therapies have many challenges due to its inconsistent potency and limited quantity. Here, we report a strategy to generate induced MSCs (iMSCs) by directly reprogramming human peripheral blood mononuclear cells (PBMCs) wit...

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Detalles Bibliográficos
Autores principales: Chen, Wanqiu, Wang, Chenguang, Yang, Zhi-Xue, Zhang, Feng, Wen, Wei, Schaniel, Christoph, Mi, Xianqiang, Bock, Matthew, Zhang, Xiao-Bing, Qiu, Hongyu, Wang, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10090171/
https://www.ncbi.nlm.nih.gov/pubmed/37041280
http://dx.doi.org/10.1038/s42003-023-04737-x