3D- and 2D-QSAR models’ study and molecular docking of novel nitrogen-mustard compounds for osteosarcoma

Background: The dipeptide-alkylated nitrogen-mustard compound is a new kind of nitrogen-mustard derivative with a strong anti-tumor activity, which can be used as a potential anti-osteosarcoma chemotherapy drug. Objective: 2D- and 3D-QSAR (structure–activity relationship quantification) models were...

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Detalles Bibliográficos
Autores principales: Zhuo, Wenkun, Lian, Zheng, Bai, Wenzhe, Chen, Yanrong, Xia, Huanling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10090277/
https://www.ncbi.nlm.nih.gov/pubmed/37065446
http://dx.doi.org/10.3389/fmolb.2023.1164349

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10090277/
https://www.ncbi.nlm.nih.gov/pubmed/37065446
http://dx.doi.org/10.3389/fmolb.2023.1164349

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