Nitric oxide augments signaling for contraction in hypoxic pulmonary arterial smooth muscle—Implications for hypoxic pulmonary hypertension

Introduction: Hypoxic persistent pulmonary hypertension in the newborn (PPHN) is usually treated with oxygen and inhaled nitric oxide (NO), both pulmonary arterial relaxants. But treatment failure with NO occurs in 25% of cases. We previously demonstrated that 72 h exposure to hypoxia, modeling PPHN...

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Detalles Bibliográficos
Autores principales: Hinton, Martha, Thliveris, James A., Hatch, Grant M., Dakshinamurti, Shyamala
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10090299/
https://www.ncbi.nlm.nih.gov/pubmed/37064915
http://dx.doi.org/10.3389/fphys.2023.1144574

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10090299/
https://www.ncbi.nlm.nih.gov/pubmed/37064915
http://dx.doi.org/10.3389/fphys.2023.1144574

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