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Computational analysis of the flexibility in the disordered linker region connecting LIM domains in cysteine–glycine-rich protein
One of the key proteins that are present in the Z-disc of cardiac tissues, CSRP3, has been implicated in dilated and hypertrophic cardiomyopathy leading to heart failure. Although multiple cardiomyopathy-related mutations have been reported to reside on the two LIM domains and the disordered regions...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10090389/ https://www.ncbi.nlm.nih.gov/pubmed/37065494 http://dx.doi.org/10.3389/fgene.2023.1134509 |