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Population pharmacokinetic analysis and dosing optimization of polymyxin B in critically ill patients
Objectives: Since the global broadcast of multidrug-resistant gram-negative bacteria is accelerating, the use of Polymyxin B is sharply increasing, especially in critically ill patients. Unsatisfactory therapeutic effects were obtained because of the abnormal physiological function in critically ill...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10090446/ https://www.ncbi.nlm.nih.gov/pubmed/37063299 http://dx.doi.org/10.3389/fphar.2023.1122310 |