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Population pharmacokinetic analysis and dosing optimization of polymyxin B in critically ill patients

Objectives: Since the global broadcast of multidrug-resistant gram-negative bacteria is accelerating, the use of Polymyxin B is sharply increasing, especially in critically ill patients. Unsatisfactory therapeutic effects were obtained because of the abnormal physiological function in critically ill...

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Detalles Bibliográficos
Autores principales:	Liang, Danhong, Liang, Zhi, Deng, Guoliang, Cen, Anfen, Luo, Dandan, Zhang, Chen, Ni, Suiqin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10090446/ https://www.ncbi.nlm.nih.gov/pubmed/37063299 http://dx.doi.org/10.3389/fphar.2023.1122310

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