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In vitro and in silico analysis of imatinib analogues as anti-Trypanosoma cruzi drug candidates

Chagas disease (CD) is a neglected tropical disease caused by the intracellular protozoan Trypanosoma cruzi that remains a serious public health issue affecting more than 6 million people worldwide. The available treatment includes 2 nitro derivatives, benznidazole (BZ) and nifurtimox, that lack in...

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Detalles Bibliográficos
Autores principales: Nesic de Freitas, Luca S. F., da Silva, Cristiane França, Intagliata, Sebastiano, Amata, Emanuele, Salerno, Loredana, Soeiro, Maria de Nazaré Correia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10090470/
https://www.ncbi.nlm.nih.gov/pubmed/36632017
http://dx.doi.org/10.1017/S0031182023000057