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ZBTB7A as a novel vulnerability in neuroendocrine prostate cancer

Neuroendocrine prostate cancer (NEPC) is a highly aggressive subtype of prostate cancer. NEPC is characterized by the loss of androgen receptor (AR) signaling and transdifferentiation toward small-cell neuroendocrine (SCN) phenotypes, which results in resistance to AR-targeted therapy. NEPC resemble...

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Detalles Bibliográficos
Autores principales: Bae, Song Yi, Bergom, Hannah E., Day, Abderrahman, Greene, Joseph T., Sychev, Zoi E., Larson, Gabrianne, Corey, Eva, Plymate, Stephen R., Freedman, Tanya S., Hwang, Justin H., Drake, Justin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10090553/
https://www.ncbi.nlm.nih.gov/pubmed/37065756
http://dx.doi.org/10.3389/fendo.2023.1093332