LDC7559 inhibits microglial activation and GSDMD-dependent pyroptosis after subarachnoid hemorrhage

Mounting evidence indicates that inhibition of microglial activation and neuronal pyroptosis plays important roles in brain function recovery after subarachnoid hemorrhage (SAH). LDC7559 is a newly discovered gasdermin D (GSDMD) inhibitor. Previous studies have demonstrated that LDC7559 could inhibi...

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Detalles Bibliográficos
Autores principales: Cai, Wenhua, Wu, Zhe, Lai, Jinqing, Yao, Jieran, Zeng, Yile, Fang, Zhongning, Lin, Weibin, Chen, Junyan, Xu, Chaoyang, Chen, Xiangrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10090682/
https://www.ncbi.nlm.nih.gov/pubmed/37063846
http://dx.doi.org/10.3389/fimmu.2023.1117310

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10090682/
https://www.ncbi.nlm.nih.gov/pubmed/37063846
http://dx.doi.org/10.3389/fimmu.2023.1117310

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