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Enhanced inhibition of protein disulfide isomerase and anti-thrombotic activity of a rutin derivative: rutin:Zn complex

Rutin is a flavonoid that exists in plants and in commonly consumed foods. In recent years, rutin has been demonstrated to have anti-thrombotic efficacy through its inhibition of protein disulfide isomerase. However, the low aqueous solubility and high dose limit the therapeutic applications of ruti...

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Detalles Bibliográficos
Autores principales: Liao, Xinyuan, Ji, Panpan, Chi, Kunxiang, Chen, Xueying, Zhou, Yang, Chen, Shanli, Cheng, Yuan, Flaumenhaft, Robert, Yuan, Cai, Huang, Mingdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10090900/
https://www.ncbi.nlm.nih.gov/pubmed/37063725
http://dx.doi.org/10.1039/d3ra01135f