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Enhanced inhibition of protein disulfide isomerase and anti-thrombotic activity of a rutin derivative: rutin:Zn complex
Rutin is a flavonoid that exists in plants and in commonly consumed foods. In recent years, rutin has been demonstrated to have anti-thrombotic efficacy through its inhibition of protein disulfide isomerase. However, the low aqueous solubility and high dose limit the therapeutic applications of ruti...
Autores principales: | Liao, Xinyuan, Ji, Panpan, Chi, Kunxiang, Chen, Xueying, Zhou, Yang, Chen, Shanli, Cheng, Yuan, Flaumenhaft, Robert, Yuan, Cai, Huang, Mingdong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10090900/ https://www.ncbi.nlm.nih.gov/pubmed/37063725 http://dx.doi.org/10.1039/d3ra01135f |
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