Cargando…

The impact of cellular senescence and senescence‑associated secretory phenotype in cancer‑associated fibroblasts on the malignancy of pancreatic cancer

Cancer-associated fibroblasts (CAFs) are implicated in the strong malignancy of pancreatic cancer (PC). Various CAF subtypes have different functions, and their heterogeneity likely influence the malignancy of PC. Meanwhile, it is known that senescent cells can create a tumor-promoting microenvironm...

Descripción completa

Detalles Bibliográficos
Autores principales: Higashiguchi, Masaya, Murakami, Hirotomo, Akita, Hirofumi, Kobayashi, Shogo, Takahama, Shokichi, Iwagami, Yoshifumi, Yamada, Daisaku, Tomimaru, Yoshito, Noda, Takehiro, Gotoh, Kunihito, Doki, Yuichiro, Yamamoto, Takuya, Eguchi, Hidetoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10091076/
https://www.ncbi.nlm.nih.gov/pubmed/36999632
http://dx.doi.org/10.3892/or.2023.8535