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The impact of cellular senescence and senescence‑associated secretory phenotype in cancer‑associated fibroblasts on the malignancy of pancreatic cancer
Cancer-associated fibroblasts (CAFs) are implicated in the strong malignancy of pancreatic cancer (PC). Various CAF subtypes have different functions, and their heterogeneity likely influence the malignancy of PC. Meanwhile, it is known that senescent cells can create a tumor-promoting microenvironm...
Autores principales: | Higashiguchi, Masaya, Murakami, Hirotomo, Akita, Hirofumi, Kobayashi, Shogo, Takahama, Shokichi, Iwagami, Yoshifumi, Yamada, Daisaku, Tomimaru, Yoshito, Noda, Takehiro, Gotoh, Kunihito, Doki, Yuichiro, Yamamoto, Takuya, Eguchi, Hidetoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10091076/ https://www.ncbi.nlm.nih.gov/pubmed/36999632 http://dx.doi.org/10.3892/or.2023.8535 |
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