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Cancer‐associated fibroblast‐derived secreted phosphoprotein 1 contributes to resistance of hepatocellular carcinoma to sorafenib and lenvatinib

BACKGROUND: Cancer‐associated fibroblasts (CAFs) play an important role in the induction of chemo‐resistance. This study aimed to clarify the mechanism underlying CAF‐mediated resistance to two tyrosine kinase inhibitors (TKIs), sorafenib and lenvatinib, and to identify a novel therapeutic target fo...

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Detalles Bibliográficos
Autores principales: Eun, Jung Woo, Yoon, Jung Hwan, Ahn, Hye Ri, Kim, Seokhwi, Kim, Young Bae, Lim, Su Bin, Park, Won, Kang, Tae Wook, Baek, Geum Ok, Yoon, Moon Gyeong, Son, Ju A, Weon, Ji Hyang, Kim, Soon Sun, Cho, Hyo Jung, Cheong, Jae Youn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10091107/
https://www.ncbi.nlm.nih.gov/pubmed/36919193
http://dx.doi.org/10.1002/cac2.12414