P38 MAPK activated ADAM17 mediates ACE2 shedding and promotes cardiac remodeling and heart failure after myocardial infarction

BACKGROUND: Heart failure (HF) after myocardial infarction (MI) is a prevalent disease with a poor prognosis. Relieving pathological cardiac remodeling and preserving cardiac function is a critical link in the treatment of post-MI HF. Thus, more new therapeutic targets are urgently needed. The expre...

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Detalles Bibliográficos
Autores principales: Chen, Qi, Li, Yilan, Bie, Bike, Zhao, Bin, Zhang, Yanxiu, Fang, Shaohong, Li, Shuijie, Zhang, Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10091339/
https://www.ncbi.nlm.nih.gov/pubmed/37046278
http://dx.doi.org/10.1186/s12964-023-01087-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10091339/
https://www.ncbi.nlm.nih.gov/pubmed/37046278
http://dx.doi.org/10.1186/s12964-023-01087-3

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