Cargando…

P38 MAPK activated ADAM17 mediates ACE2 shedding and promotes cardiac remodeling and heart failure after myocardial infarction

BACKGROUND: Heart failure (HF) after myocardial infarction (MI) is a prevalent disease with a poor prognosis. Relieving pathological cardiac remodeling and preserving cardiac function is a critical link in the treatment of post-MI HF. Thus, more new therapeutic targets are urgently needed. The expre...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Qi, Li, Yilan, Bie, Bike, Zhao, Bin, Zhang, Yanxiu, Fang, Shaohong, Li, Shuijie, Zhang, Yao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10091339/ https://www.ncbi.nlm.nih.gov/pubmed/37046278 http://dx.doi.org/10.1186/s12964-023-01087-3

Ejemplares similares

A model for COVID-19-induced dysregulation of ACE2 shedding by ADAM17
por: Healy, Eamonn F., et al.
Publicado: (2021)

ADAM17 knockdown mitigates while ADAM17 overexpression aggravates cardiac fibrosis and dysfunction via regulating ACE2 shedding and myofibroblast transformation
por: Cheng, Jing, et al.
Publicado: (2022)

ADAM17 Mediates Hypoxia-Induced Keratinocyte Migration via the p38/MAPK Pathway
por: Zhu, Guoqin, et al.
Publicado: (2021)

The collectrin‐like part of the SARS‐CoV‐1 and ‐2 receptor ACE2 is shed by the metalloproteinases ADAM10 and ADAM17
por: Niehues, Rabea Victoria, et al.
Publicado: (2022)

Activation of Kinin B1R Upregulates ADAM17 and Results in ACE2 Shedding in Neurons
por: Parekh, Rohan Umesh, et al.
Publicado: (2020)

LRP1 shedding in human brain: roles of ADAM10 and ADAM17
por: Liu, Qiang, et al.
Publicado: (2009)

Dynamics of ADAM17-Mediated Shedding of ACE2 Applied to Pancreatic Islets of Male db/db Mice
por: Pedersen, Kim Brint, et al.
Publicado: (2015)

ADAM17-Mediated Shedding of Inflammatory Cytokines in Hypertension
por: de Queiroz, Thyago M., et al.
Publicado: (2020)

Distinct roles for ADAM10 and ADAM17 in ectodomain shedding of six EGFR ligands
por: Sahin, Umut, et al.
Publicado: (2004)

miR-145 Alleviates Smooth Muscle Cell Phenotype Transition via ADAM17-Mediated ACE2 Shedding
por: Wen, Juan, et al.
Publicado: (2023)

ADAM10 mediates shedding of carbonic anhydrase IX ectodomain non-redundantly to ADAM17
por: Zatovicova, Miriam, et al.
Publicado: (2022)

How tetraspanin-mediated cell entry of SARS-CoV-2 can dysregulate the shedding of the ACE2 receptor by ADAM17
por: Healy, Eamonn F.
Publicado: (2022)

Higher serum phosphorus and calcium levels provide prognostic value in patients with acute myocardial infarction
por: Cao, Wei, et al.
Publicado: (2022)

ADAM17 is essential for ectodomain shedding of the EGF‐receptor ligand amphiregulin
por: Hosur, Vishnu, et al.
Publicado: (2018)

Involvement of shedding induced by ADAM17 on the nitric oxide pathway in hypertension
por: da Silva, Mirelly Cunha, et al.
Publicado: (2022)

Corrigendum: Higher serum phosphorus and calcium levels provide prognostic value in patients with acute myocardial infarction
por: Cao, Wei, et al.
Publicado: (2022)

SIRT1 mediates the inhibitory effect of Dapagliflozin on EndMT by inhibiting the acetylation of endothelium Notch1
por: Wang, Weijie, et al.
Publicado: (2023)

ADAM17 mediates ectodomain shedding of the soluble VLDL receptor fragment in the retinal epithelium
por: Ma, Xiang, et al.
Publicado: (2021)

Targeting cardiomyocyte ADAM10 ectodomain shedding promotes survival early after myocardial infarction
por: Klapproth, Erik, et al.
Publicado: (2022)

IL-33 attenuates cardiac remodeling following myocardial infarction via inhibition of the p38 MAPK and NF-κB pathways
por: Yin, Honglei, et al.
Publicado: (2022)

Differences in Shedding of the Interleukin-11 Receptor by the Proteases ADAM9, ADAM10, ADAM17, Meprin α, Meprin β and MT1-MMP
por: Sammel, Martin, et al.
Publicado: (2019)

A Mechanism of Male Germ Cell Apoptosis Induced by Bisphenol-A and Nonylphenol Involving ADAM17 and p38 MAPK Activation
por: Urriola-Muñoz, Paulina, et al.
Publicado: (2014)

Dendritic Cell-Restricted Progenitors Contribute to Obesity-Associated Airway Inflammation via Adam17-p38 MAPK-Dependent Pathway
por: Jaiswal, Anil Kumar, et al.
Publicado: (2020)

Tetraspanin CD9 modulates ADAM17-mediated shedding of LR11 in leukocytes
por: Tsukamoto, Shokichi, et al.
Publicado: (2014)

Lung ACE2 and ADAM17 in pulmonary arterial hypertension: Implications for COVID-19?
por: Pérez-Vizcaíno, Francisco
Publicado: (2020)

The role of S100B/RAGE-enhanced ADAM17 activation in endothelial glycocalyx shedding after traumatic brain injury
por: Zou, Zhimin, et al.
Publicado: (2022)

Fractalkine shedding is mediated by p38 and the ADAM10 protease under pro-inflammatory conditions in human astrocytes
por: O’Sullivan, Sinead A., et al.
Publicado: (2016)

Phosphorylation of iRhom2 Controls Stimulated Proteolytic Shedding by the Metalloprotease ADAM17/TACE
por: Cavadas, Miguel, et al.
Publicado: (2017)

Ectodomain Shedding by ADAM17: Its Role in Neutrophil Recruitment and the Impairment of This Process during Sepsis
por: Mishra, Hemant K., et al.
Publicado: (2017)

ADAM17-mediated EGFR ligand shedding directs macrophage-promoted cancer cell invasion
por: Gnosa, Sebastian P., et al.
Publicado: (2022)

Cardiac Fibroblast p38 MAPK: A Critical Regulator of Myocardial Remodeling
por: Turner, Neil A., et al.
Publicado: (2019)

Interleukin‐38 alleviates cardiac remodelling after myocardial infarction
por: Wei, Yuzhen, et al.
Publicado: (2019)

p38 MAPK Signaling in Postnatal Tendon Growth and Remodeling
por: Schwartz, Andrew J., et al.
Publicado: (2015)

Potential role of a disintegrin and metalloproteinase-17 (ADAM17) in age-associated ventricular remodeling of rats
por: Liu, Hainiang, et al.
Publicado: (2019)

ADAM 17 endopeptidase
Publicado: (2009)

ACE2/ADAM17/TMPRSS2 Interplay May Be the Main Risk Factor for COVID-19
por: Zipeto, Donato, et al.
Publicado: (2020)

The ADAM15 ectodomain is shed from secretory exosomes
por: Lee, Hee Doo, et al.
Publicado: (2015)

Regulation of ectodomain shedding of ADAM33 in vitro and in vivo
por: Davies, Elizabeth R., et al.
Publicado: (2019)

Effects of atorvastatin on p38 phosphorylation and cardiac remodeling after myocardial infarction in rats
por: Li, Mingyang, et al.
Publicado: (2018)

Cardiomyocyte-specific knockout of ADAM17 ameliorates left ventricular remodeling and function in diabetic cardiomyopathy of mice
por: Xue, Fei, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_tcebbreh8v3ddb9ee3tkvf63bo