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Modeling the Orthosteric Binding Site of the G Protein-Coupled Odorant Receptor OR5K1

[Image: see text] With approximately 400 encoding genes in humans, odorant receptors (ORs) are the largest subfamily of class A G protein-coupled receptors (GPCRs). Despite its high relevance and representation, the odorant-GPCRome is structurally poorly characterized: no experimental structures are...

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Detalles Bibliográficos
Autores principales: Nicoli, Alessandro, Haag, Franziska, Marcinek, Patrick, He, Ruiming, Kreißl, Johanna, Stein, Jörg, Marchetto, Alessandro, Dunkel, Andreas, Hofmann, Thomas, Krautwurst, Dietmar, Di Pizio, Antonella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10091413/
https://www.ncbi.nlm.nih.gov/pubmed/36696962
http://dx.doi.org/10.1021/acs.jcim.2c00752