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Maternal zinc alleviates tert-butyl hydroperoxide-induced mitochondrial oxidative stress on embryonic development involving the activation of Nrf2/PGC-1α pathway

BACKGROUND: Mitochondrial dysfunction induced by excessive mitochondrial reactive oxygen species (ROS) damages embryonic development and leads to growth arrest. OBJECTIVE: The purpose of this study is to elucidate whether maternal zinc (Zn) exert protective effect on oxidative stress targeting mitoc...

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Detalles Bibliográficos
Autores principales: Huang, Liang, Gao, Wei, He, Xuri, Yuan, Tong, Zhang, Huaqi, Zhang, Xiufen, Zheng, Wenxuan, Wu, Qilin, Liu, Ju, Wang, Wence, Yang, Lin, Zhu, Yongwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10091542/
https://www.ncbi.nlm.nih.gov/pubmed/37041604
http://dx.doi.org/10.1186/s40104-023-00852-1