Inactivation of RB1 , CDKN2A , and TP53 have distinct effects on genomic stability at side‐by‐side comparison in karyotypically normal cells

Chromosomal instability is a common feature in malignant tumors. Previous studies have indicated that inactivation of the classical tumor suppressor genes RB1, CDKN2A, and TP53 may contribute to chromosomal aberrations in cancer by disrupting different aspects of the cell cycle and DNA damage checkp...

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Detalles Bibliográficos
Autores principales: Andersson, Natalie, Saba, Karim H., Magnusson, Linda, Nilsson, Jenny, Karlsson, Jenny, Nord, Karolin H., Gisselsson, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10091693/
https://www.ncbi.nlm.nih.gov/pubmed/36124964
http://dx.doi.org/10.1002/gcc.23096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10091693/
https://www.ncbi.nlm.nih.gov/pubmed/36124964
http://dx.doi.org/10.1002/gcc.23096

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