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Inactivation of RB1 , CDKN2A , and TP53 have distinct effects on genomic stability at side‐by‐side comparison in karyotypically normal cells
Chromosomal instability is a common feature in malignant tumors. Previous studies have indicated that inactivation of the classical tumor suppressor genes RB1, CDKN2A, and TP53 may contribute to chromosomal aberrations in cancer by disrupting different aspects of the cell cycle and DNA damage checkp...
Autores principales: | Andersson, Natalie, Saba, Karim H., Magnusson, Linda, Nilsson, Jenny, Karlsson, Jenny, Nord, Karolin H., Gisselsson, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10091693/ https://www.ncbi.nlm.nih.gov/pubmed/36124964 http://dx.doi.org/10.1002/gcc.23096 |
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