Sirt3 Promotes Chondrogenesis, Chondrocyte Mitochondrial Respiration and the Development of High‐Fat Diet‐Induced Osteoarthritis in Mice

Understanding how obesity‐induced metabolic stress contributes to synovial joint tissue damage is difficult because of the complex role of metabolism in joint development, maintenance, and repair. Chondrocyte mitochondrial dysfunction is implicated in osteoarthritis (OA) pathology, which motivated u...

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Detalles Bibliográficos
Autores principales: Zhu, Shouan, Donovan, Elise L., Makosa, Dawid, Mehta‐D'souza, Padmaja, Jopkiewicz, Anita, Batushansky, Albert, Cortassa, Dominic, Simmons, Aaron D., Lopes, Erika Barboza Prado, Kinter, Michael, Griffin, Timothy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10091721/
https://www.ncbi.nlm.nih.gov/pubmed/36214465
http://dx.doi.org/10.1002/jbmr.4721

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10091721/
https://www.ncbi.nlm.nih.gov/pubmed/36214465
http://dx.doi.org/10.1002/jbmr.4721

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