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Sirt3 Promotes Chondrogenesis, Chondrocyte Mitochondrial Respiration and the Development of High‐Fat Diet‐Induced Osteoarthritis in Mice
Understanding how obesity‐induced metabolic stress contributes to synovial joint tissue damage is difficult because of the complex role of metabolism in joint development, maintenance, and repair. Chondrocyte mitochondrial dysfunction is implicated in osteoarthritis (OA) pathology, which motivated u...
Autores principales: | Zhu, Shouan, Donovan, Elise L., Makosa, Dawid, Mehta‐D'souza, Padmaja, Jopkiewicz, Anita, Batushansky, Albert, Cortassa, Dominic, Simmons, Aaron D., Lopes, Erika Barboza Prado, Kinter, Michael, Griffin, Timothy M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10091721/ https://www.ncbi.nlm.nih.gov/pubmed/36214465 http://dx.doi.org/10.1002/jbmr.4721 |
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