A cytotoxic survey on 2‐amino‐1H‐imidazol based synthetic marine sponge alkaloid analogues

Here, we describe the synthesis and biologic activity evaluation of 20 novel synthetic marine sponge alkaloid analogues with 2‐amino‐1H‐imidazol (2‐AI) core. Cytotoxicity was tested on murine 4T1 breast cancer, A549 human lung cancer, and HL‐60 human myeloid leukemia cells by the resazurin assay. A...

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Detalles Bibliográficos
Autores principales: Gémes, Nikolett, Makra, Zsófia, Neuperger, Patrícia, Szabó, Enikő, Balog, József Á., Flink, Lili Borbála, Kari, Beáta, Hackler, László, Puskás, László. G., Kanizsai, Iván, Szebeni, Gábor J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10091778/
https://www.ncbi.nlm.nih.gov/pubmed/36322473
http://dx.doi.org/10.1002/ddr.22006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10091778/
https://www.ncbi.nlm.nih.gov/pubmed/36322473
http://dx.doi.org/10.1002/ddr.22006

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