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Complement component C3 and C5b‐9 deposition on hypoxia reperfused endothelial cells by non‐HLA antibodies against RhoGDI2: A player involved in graft failure?

Antibodies against Rho GDP‐dissociation inhibitor 2 (RhoGDI2) are associated with inferior graft survival in transplant patients receiving a kidney from deceased donors. Although this suggests that these antibodies contribute to graft injury because of ischemia, it remains unknown whether they are a...

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Detalles Bibliográficos
Autores principales: Kardol‐Hoefnagel, Tineke, Michielsen, Laura A., Ehlers, Anna M., van Zuilen, Arjan D., Luijk, Bart, Otten, Henny G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10091817/
https://www.ncbi.nlm.nih.gov/pubmed/36266772
http://dx.doi.org/10.1111/tan.14858