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Tumor protease-activated theranostic nanoparticles for MRI-guided glioblastoma therapy

Rationale: As a cancer, Glioblastoma (GBM) is a highly lethal and difficult-to-treat. With the aim of improving therapies to GBM, we developed novel and target-specific theranostic nanoparticles (TNPs) that can be selectively cleaved by cathepsin B (Cat B) to release the potent toxin monomethyl auri...

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Detalles Bibliográficos
Autores principales: Huang, Ching-Hsin, Chang, Edwin, Zheng, Li, Raj, Joe Gerald Jesu, Wu, Wei, Pisani, Laura J., Daldrup-Link, Heike E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10091873/
https://www.ncbi.nlm.nih.gov/pubmed/37064879
http://dx.doi.org/10.7150/thno.79342