Single-cell profiling of GP2-enriched pancreatic progenitors to simultaneously create acinar, ductal, and endocrine organoids

Rationale: Pancreatic lineage specification follows the formation of tripotent pancreatic progenitors (PPs). Current protocols rebuilding PPs in vitro have an endocrine lineage bias and are mostly based on PDX1/NKX6-1 coexpression neglecting other markers decisive for PP heterogeneity and lineage po...

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Detalles Bibliográficos
Autores principales: Merz, Sarah, Breunig, Markus, Melzer, Michael Karl, Heller, Sandra, Wiedenmann, Sandra, Seufferlein, Thomas, Meier, Matthias, Krüger, Jana, Mulaw, Medhanie A, Hohwieler, Meike, Kleger, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10091881/
https://www.ncbi.nlm.nih.gov/pubmed/37064874
http://dx.doi.org/10.7150/thno.78323

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10091881/
https://www.ncbi.nlm.nih.gov/pubmed/37064874
http://dx.doi.org/10.7150/thno.78323

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