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Platelets promote CRC by activating the C5a/C5aR1 axis via PSGL-1/JNK/STAT1 signaling in tumor-associated macrophages

Rationale: Platelets can influence the progression and prognosis of colorectal cancer (CRC) through multiple mechanisms, including crosstalk with tumor-associated macrophages (TAMs). However, the mechanisms underlying the crosstalk between platelets and TAMs remain unclear. The present study aimed t...

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Detalles Bibliográficos
Autores principales: Li, Xueqin, Chen, Xin, Gong, Shengzhe, Zhao, Jie, Yao, Chen, Zhu, Hanyong, Xiao, Rui, Qin, Yongqin, Li, Rongqing, Sun, Na, Li, Xiangyang, Dong, Fuxing, Zhao, Tingting, Pan, Yuchen, Yang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10091882/
https://www.ncbi.nlm.nih.gov/pubmed/37064877
http://dx.doi.org/10.7150/thno.80555